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WT-161

CAT: 0013-GTR19164309-01Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19164309-01Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A potent, selective, and bioavailable HDAC6 inhibitor with IC50 0.4 nM; displays >20-fold selectivity over HDAC1/2/3/8; selectively inhibits HDAC6 and dramatically increases levels of acetylated α-tubulin with little effect on global lysine acetylation in cells; reversibly and rapidly induces the accumulation of Ac-α-tubulin in MM cell lines, displays synergism with both BTZ and CFZ, caspase activation and apoptosis; demonstrates a significant antitumor effect in human MM cell xenograft mouse model combined with BTZ.
CAS Number
1206731-57-8
Product Name Alternative
WT 161 | WT161
Purity
>98% (HPLC)
Solubility
DMSO : ≥ 100 mg/mL 218.08 mM
Smiles
O=C (NO) CCCCCCC (N/N=C/C1=CC=C (N (C2=CC=CC=C2) C3=CC=CC=C3) C=C1) =O
Molecular Formula
C27H30N4O3
Molecular Weight
458.55
Storage Conditions
Storage temperature: -20°C. Stability: ≥ 2 years
Notes
For research use only.
Other Product Names
Octanoic acid, 8- (hydroxyamino) -8-oxo-, 2-[[4- (diphenylamino) phenyl]methylene]hydrazide

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Alternative Products

CatalogName
BA1597-100WT-161
A20432-5WT-161 5mg
A20432-1WT-161 1mg
HY-100871RWT-161 (Standard)
A20432-50WT-161 50mg
A20432-10WT-161 10mg
A20432-2WT-161 2mg
A20432-100WT-161 100mg
A20432-25WT-161 25mg
A20432-10mM-DWT-161 10mM * 1mL in DMSO

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