V-161

• Target :

  ATPase|||Antibacterial

• Related Pathways :

  Membrane transporter/Ion channel|||Microbiology/Virology

• Bioactivity :

  V-161 is an orally active Na+-V-ATPase inhibitor with an IC50 of 144 nM. Under alkaline conditions, V-161 inhibits Enterococcus hirae and vancomycin-resistant Enterococcus faecium (VRE), with MIC values of 4 µg/mL for both. Additionally, V-161 can inhibit the colonization of VRE in the mouse small intestine.

• Smiles :

  N=1C2=CC(=CC=C2NC1C=3C=CC(=CC3)N(C)C)C

• Molecular Formula :

  C16H17N3

• Molecular Weight :

  251.326

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  69570-95-2