RTx-161

CAT: 0013-GTR19262365-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19262365-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

RTx-161 is an allosteric Polθ polymerase inhibitor with an IC50 value of 4.1 nM. It selectively kills HR-deficient cancer cells and inhibits PARP inhibitor (PARPi) resistance across various genetic backgrounds, including HR-proficient cells. RTx-161 also induces apoptosis.

Field of Research

Cell Biology, Molecular Biology

Molecular Formula

C21H18F7N3O4

Storage Conditions

-20°C

Notes

For research use only.

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RTx-161

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