RTx-161

CAT: 0931-MF-0117150-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0117150-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis|||DNA/RNA Synthesis
Related Pathways
Apoptosis|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair
Bioactivity
RTx-161 is an allosteric Pol? polymerase inhibitor with an IC50 value of 4.1 nM. It selectively kills HR-deficient cancer cells and inhibits PARP inhibitor (PARPi) resistance across various genetic backgrounds, including HR-proficient cells. RTx-161 also induces apoptosis.
Molecular Formula
C21H18F7N3O4
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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