AB-161

• Target:

  HBV

• Related Pathways:

  Microbiology/Virology

• Bioactivity:

  AB-161 is an orally active destabilizer of HBV RNA and an inhibitor of PAPD5/7, primarily targeting the liver. It treats hepatitis B virus (HBV) infection by reducing hepatitis B surface antigen (HBsAg) levels, exhibiting an EC50 value of 2.2 nM for HBsAg. AB-161 is applicable in HBV infection research.

• Smiles:

  C(C)(C)(C)[C@@H]1CC2=C(C3=C1C=C(C(O)=O)C(=O)N3)N=C4N2C=C(OC)C=C4OC(F)F

• Molecular Formula:

  C21H21F2N3O5

• Molecular Weight:

  433.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2848560-66-5