STAT3-IN-14

• UNSPSC Description:

  STAT3-IN-14 (Compound 1) is a STAT3 inhibitor and has STAT3 phosphorylation inhibitory activity. STAT3-IN-14 (Compound 1) can directly bind to the hinge region of STAT3[1].

• Target Antigen:

  STAT

• Type:

  Natural Products

• Related Pathways:

  JAK/STAT Signaling;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/stat3-in-14.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=C2OC([C@@H](O)C)=C1)C3=C(C2=O)C=CC=C3O

• Molecular Weight:

  258.23

• References & Citations:

  [1]Teruyuki Tahara, et al. STAT3 inhibitory activity of naphthoquinones isolated from Tabebuia avellanedae. Bioorg Med Chem. 2020 Mar 15;28(6):115347.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  123297-90-5