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STAT3-IN-9

CAT: 0804-HY-146666Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-146666Size:1 Each
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Description
STAT3-IN-9 is a potent STAT3 inhibitor. STAT3-IN-9 inhibits the activation of STAT3 (Tyr705) without influencing the phosphorylation of STAT1 (Tyr701) . STAT3-IN-9 induces apoptosis and cell cycle arrest at the G2/M phase[1].
CAS Number
2987726-27-0
UNSPSC
12352005
Target
Apoptosis; STAT
Type
Reference compound
Related Pathways
Apoptosis; JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stat3-in-9.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(NC2=CC(C3=CC=NN3C)=CC4=C2OC(C(C)=O)=C4)=CC(OC)=C1
Molecular Formula
C22H21N3O4
Molecular Weight
391.42
References & Citations
[1]Wang F, et al. Identification of novel STAT3 inhibitors bearing 2-acetyl-7-phenylamino benzofuran scaffold for antitumour study. Bioorg Med Chem. 2020; 28 (24) :115822.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT3

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