STAT3-IN-9

STAT3-IN-9

• CAS Number: 2987726-27-0
• UNSPSC Description: STAT3-IN-9 is a potent STAT3 inhibitor. STAT3-IN-9 inhibits the activation of STAT3 (Tyr705) without influencing the phosphorylation of STAT1 (Tyr701). STAT3-IN-9 induces apoptosis and cell cycle arrest at the G2/M phase[1].
• Target Antigen: Apoptosis; STAT
• Type: Reference compound
• Related Pathways: Apoptosis;JAK/STAT Signaling;Stem Cell/Wnt
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/stat3-in-9.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=CC(NC2=CC(C3=CC=NN3C)=CC4=C2OC(C(C)=O)=C4)=CC(OC)=C1
• Molecular Weight: 391.42
• References & Citations: [1]Wang F, et al. Identification of novel STAT3 inhibitors bearing 2-acetyl-7-phenylamino benzofuran scaffold for antitumour study. Bioorg Med Chem. 2020; 28(24):115822.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported