STAT3-IN-7

• Description :

  STAT3-IN-7, an aryl sulfonamido azetidine compound, is an orally active STAT3 inhibitor. STAT3-IN-7 has anticancer activities (WO2021016333A1, H182) [1].

• UNSPSC :

  12352005

• Target :

  STAT

• Type :

  Reference compound

• Related Pathways :

  JAK/STAT Signaling; Stem Cell/Wnt

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/stat3-in-7-1.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1NC=NC2=C1C=CC(N(C([C@H]3CCN3S(=O)(C4=C(C(F)=C(C(F)=C4F)F)F)=O)=O)CC5=CC=C(C=N5)C6CCCCC6)=C2

• Molecular Formula :

  C30H26F5N5O4S

• Molecular Weight :

  647.62

• References & Citations :

  [1]James Turkson, et al. Aryl sulfonamides as small molecule stat3 inhibitors. WO2021016333A1.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2237955-91-6]