STAT3-IN-7

• UNSPSC Description:

  STAT3-IN-7, an aryl sulfonamido azetidine compound, is an orally active STAT3 inhibitor. STAT3-IN-7 has anticancer activities (WO2021016333A1, H182)[1].

• Target Antigen:

  STAT

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/stat3-in-7-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NC=NC2=C1C=CC(N(C([C@H]3CCN3S(=O)(C4=C(C(F)=C(C(F)=C4F)F)F)=O)=O)CC5=CC=C(C=N5)C6CCCCC6)=C2

• Molecular Weight:

  647.62

• References & Citations:

  [1]James Turkson, et al. Aryl sulfonamides as small molecule stat3 inhibitors. WO2021016333A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2237955-91-6