STAT3-IN-29

• UNSPSC Description:

  STAT3-IN-29 (Compound B20) is an inhibitor for STAT3. STAT3-IN-29 inhibits the proliferation of HaCaT cell with IC50 of 0.09 µM, ameliorates the IMQ-induced psoriasis in mouse models[1].

• Target Antigen:

  STAT

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling;Stem Cell/Wnt

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/stat3-in-29.html

• Smiles:

  COC(C=C1)=C(OC)C=C1CC2=NOC3=C2C(C4=C(O)C=CC=C4C3=O)=O

• Molecular Weight:

  365.34

• References & Citations:

  [1]Chen L, et al. Synthesis and biological evaluation of novel isoxazoloquinone derivatives as potent STAT3-targeting antipsoriasis agents[J]. Bioorganic Chemistry, 2024: 107617.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2256751-16-1