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STAT3-IN-29

CAT: 0804-HY-161864Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161864Size:1 Each
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Description
STAT3-IN-29 (Compound B20) is an inhibitor for STAT3. STAT3-IN-29 inhibits the proliferation of HaCaT cell with IC50 of 0.09 µM, ameliorates the IMQ-induced psoriasis in mouse models[1].
CAS Number
2256751-16-1
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/stat3-in-29.html
Smiles
COC(C=C1)=C(OC)C=C1CC2=NOC3=C2C(C4=C(O)C=CC=C4C3=O)=O
Molecular Formula
C20H15NO6
Molecular Weight
365.34
References & Citations
[1]Chen L, et al. Synthesis and biological evaluation of novel isoxazoloquinone derivatives as potent STAT3-targeting antipsoriasis agents[J]. Bioorganic Chemistry, 2024: 107617.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
STAT3

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