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STAT3-IN-4

CAT: 0804-HY-123524-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-123524-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STAT3-IN-4 (compound B9) is a STAT3 inhibitor with Kd values for STAT3 (I634S/Q635G) and WT are 22.75 and 4.59 μM, respectively. STAT3-IN-4 can inhibit the proliferation of tumor cells[1].
CAS Number
825611-06-1
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/stat3-in-4.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=C(C(C2=C3C=CC=C2)=O)C(C3=O)=C1)(NC4=CC=C(C=C4)O)=O
Molecular Formula
C20H13NO5S
Molecular Weight
379.39
References & Citations
[1]Huang M, et al. Screening and biological evaluation of a novel STAT3 signaling pathway inhibitor against cancer. Bioorg Med Chem Lett. 2016 Nov 1;26 (21) :5172-5176.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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