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PROTAC SMARCA2 degrader-3

CAT: 0013-GTR19234720-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234720-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC SMARCA2 degrader-3 (Compound 153) is a heterobifunctional small molecule that selectively targets and degrades the SMARCA2 (BRM) ATPase subunit of the SWI/SNF chromatin remodeling complex. It is a valuable chemical probe for investigating SWI/SNF biology and has demonstrated anticancer activity in both cellular and in vivo preclinical studies.
CAS Number
3024266-69-8
Field of Research
Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C1C (N2C=3C (=C (C=CC3) [C@@H]4CC[C@@H] (CC4) N5CCC (CC5) N6C=C (C=N6) C=7C=C (N=NC7N) C8=C (O) C=CC=C8) OCC2) CCC (=O) N1
Molecular Formula
C37H42N8O4
Molecular Weight
662.78
Storage Conditions
-20°C
Notes
For research use only.

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