PROTAC SMARCA2 degrader-23

• UNSPSC Description:

  PROTAC SMARCA2 degrader-23 (Example 1) is a potent and selective PROTAC SMARCA2 degrader, with a DC50 of [1].

• Target Antigen:

  Epigenetic Reader Domain; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-smarca2-degrader-23.html

• Smiles:

  O=C([C@@H](C1=CC(OCCN2CC(N3CCC4(C5=CC(C6=CC=CC=C6O)=NN=C5NC4)CC3)CC2)=NO1)C(C)C)N7C[C@H](O)C[C@H]7C(N[C@@H](C)C8=CC=C(C9=C(C)N=CS9)C=C8)=O

• Molecular Weight:

  876.08

• References & Citations:

  [1]Lu L, et, al. Brm targeting compounds and associated methods of use. WO2023287787A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2892523-67-8