PROTAC SMARCA2/4-degrader-3

PROTAC SMARCA2/4-degrader-3

• CAS Number: 2568507-10-6
• UNSPSC Description: SMARCA2/4-degrader-3 (compound I-433) is a PROTAC SMARCA2/4-degrader based on VH032-NH2, with a degradation potency (DC50) [1].
• Target Antigen: PROTACs
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-smarca2-4-degrader-3.html
• Smiles: O=C([C@H]1N(C[C@H](O)C1)C([C@@H](NC(C2CC3(CC(C4=CC=C(CN5CCC(CC5)CN6N=CC(C7=C(N)N=NC(C8=C(O)C=CC=C8)=C7)=C6)C=C4)C3)C2)=O)C(C)(C)C)=O)NCC9=CC=C(C%10=C(C)N=CS%10)C=C9
• Molecular Weight: 991.25
• References & Citations: [1]Nan J, et al. Smarca degraders and uses thereof, US20230072658A1, 2023-03-09
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported