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PROTAC SMARCA2 degrader-10

CAT: 0013-GTR19238677-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238677-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC SMARCA2 degrader-10 (I-507) is a potent and selective small molecule degrader of the SMARCA2 (BRM) protein. It achieves over 90% degradation (Dmax >90%) with a DC50 below 100 nM in A549 cells within 24 hours. This tool compound is valuable for probing SMARCA2 biology in cancer research and for targeted protein degradation studies both in vitro and in vivo.
CAS Number
2568279-34-3
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
C ([C@@H] (NC (=O) C1=CC=C (C=C1) C2=CC=C (CN3CCC (CN4C=C (C=N4) C=5C=C (N=NC5N) C6=C (O) C=CC=C6) CC3) C=C2) C (C) (C) C) (=O) N7[C@H] (C (NCC8=CC=C (C=C8) C9=C (C) N=CS9) =O) C[C@@H] (O) C7
Molecular Formula
C55H60N10O5S
Molecular Weight
973.19
Storage Conditions
-20°C
Notes
For research use only.

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