PROTAC SMARCA2 degrader-3

• UNSPSC Description:

  PROTAC SMARCA2 degrader-3 is a PROTAC degrader of the SWI/SNF ATPase subunits, SMARCA2. PROTAC SMARCA2 degrader-3 has anticancer effects (WO2023244764A1; Compound 153)[1].

• Target Antigen:

  Epigenetic Reader Domain; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-smarca2-degrader-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  NC1=C(C=C(C2=CC=CC=C2O)N=N1)C(C=N3)=CN3C(CC4)CCN4[C@@H](CC5)CC[C@@H]5C6=C(OCCN7C8C(NC(CC8)=O)=O)C7=CC=C6

• Molecular Weight:

  662.78

• References & Citations:

  [1]Christopher G., et al. Compounds for the targeted degradation of smarca2. WO2023244764A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3024266-69-8