PROTAC SMARCA2 degrader-27

• UNSPSC Description:

  PROTAC SMARCA2 degrader-27 (compound 4) is a PROTAC SMARCA2 degrader. PROTAC SMARCA2 degrader-27 has the potential to be used in cancer research (blue: VHL ligand (HY-168232); black: linker, (HY-168231); pink: SMARCA2 ligand, (HY-168230))[1].

• Target Antigen:

  Epigenetic Reader Domain; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-smarca2-degrader-27.html

• Smiles:

  NC(N=N1)=C(N2CC3N(C4=CC(O[C@@H]5C[C@@H](OC6CCN(CC7CCN(C8=NOC([C@H](C(N9C[C@H](O)C[C@H]9C(N[C@H](C%10=CC(F)=C(C#N)C=C%10)C)=O)=O)C(C)C)=C8)CC7)CC6)C5)=NC=C4)C(CC3)C2)C=C1C%11=CC=CC=C%11O

• Molecular Weight:

  1067.26

• References & Citations:

  [1]Michael Berlin, et al. Brm targeting compounds and associated methods of use. WO2023097031.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2410314-57-5