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PROTAC SMARCA2 degrader-28

CAT: 0013-GTR19240411-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19240411-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC SMARCA2 degrader-28 (Compound 158) is a highly potent, cell-permeable degrader of the SMARCA2 (BRM) protein, demonstrating a DC50 of 3 nM in HiBiT-tagged A549 lung cancer cells. This tool compound enables the study of SMARCA2 biology and its therapeutic potential in oncology research, both in vitro and in vivo.
CAS Number
2641510-88-3
Field of Research
Epigenetics & Chromatin, Neuroscience, Pharmacology & Drug Discovery
Smiles
O=C (C (F) (F) F) O.O=C1C2=CC=C (N3CCC (CC3) C (N4CCN (CC4) CC5=CC (N6C7CN (CC6CC7) C8=C (N) N=NC (C9=CC (F) =CC=C9O) =C8) =CC=C5) =O) C=C2C (N1C%10C (NC (CC%10) =O) =O) =O.O=C (C (F) (F) F) O
Molecular Formula
C50H51F7N10O10
Molecular Weight
1084.99
Storage Conditions
-20°C
Notes
For research use only.

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