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α1A-AR Degrader 9c

CAT: 0013-GTR19221137Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19221137Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The compound 9c is a potent, selective, and reversible PROTAC degrader of the α1A adrenergic receptor (DC50 = 2.86 μM) . It induces proteasomal degradation of the target, demonstrating anti-proliferative activity (IC50 = 6.12 μM in PC-3 cells) and potential for prostate cancer research.
CAS Number
2863635-02-1
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Smiles
N (C (COCCOCCOCCN1C=C (C (=O) N2CCN (CC2) C3=NC4=C (C (N) =N3) C=C (OC) C (OC) =C4) N=N1) =O) C5=C6C (C (=O) N (C6=O) C7C (=O) NC (=O) CC7) =CC=C5
Molecular Formula
C38H43N11O11
Molecular Weight
829.82
Storage Conditions
-20°C
Notes
For research use only.

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