PROTAC AR Degrader-4
CAT:
804-HY-111848
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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PROTAC AR Degrader-4
UNSPSC Description:
PROTAC AR Degrader-4 comprises a IAP ligand binding group, a linker and an Androgen Receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].Target Antigen:
Androgen Receptor; PROTACs; SNIPERsType:
Reference compoundRelated Pathways:
PROTAC;Vitamin D Related/Nuclear ReceptorApplications:
Cancer-programmed cell deathField of Research:
CancerAssay Protocol:
https://www.medchemexpress.com/protac-ar-degrader-4.htmlSmiles:
O=C1CC[C@@]2(C)[C@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4OC(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC5=CC=CC=C5)=O)=O)=O)([H])C1Molecular Weight:
770.01References & Citations:
[1]Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.Shipping Conditions:
Room temperatureClinical Information:
No Development ReportedCAS Number:
1351169-31-7