PROTAC AR Degrader-4

CAT:
804-HY-111848
Size:
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
PROTAC AR Degrader-4 - image 1

PROTAC AR Degrader-4

  • UNSPSC Description:

    PROTAC AR Degrader-4 comprises a IAP ligand binding group, a linker and an Androgen Receptor (AR) binding group. PROTAC AR Degrader-4 is an AR degrader. Degradation inducers based on cIAP1 are called specific and non-genetic IAP-dependent protein erasers (SNIPERs)[1].
  • Target Antigen:

    Androgen Receptor; PROTACs; SNIPERs
  • Type:

    Reference compound
  • Related Pathways:

    PROTAC;Vitamin D Related/Nuclear Receptor
  • Applications:

    Cancer-programmed cell death
  • Field of Research:

    Cancer
  • Assay Protocol:

    https://www.medchemexpress.com/protac-ar-degrader-4.html
  • Smiles:

    O=C1CC[C@@]2(C)[C@](CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4OC(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@H](N)CC5=CC=CC=C5)=O)=O)=O)([H])C1
  • Molecular Weight:

    770.01
  • References & Citations:

    [1]Itoh Y, et al. Design, synthesis and biological evaluation of nuclear receptor-degradation inducers. Bioorg Med Chem. 2011 Nov 15;19(22):6768-78.
  • Shipping Conditions:

    Room temperature
  • Clinical Information:

    No Development Reported
  • CAS Number:

    1351169-31-7