Products for Research Use Only

PROTAC AR Degrader-8

CAT: 0013-GTR19250341-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19250341-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC AR Degrader-8 (NP18) is a bifunctional degrader that potently targets both full-length and AR-V7 splice variant androgen receptors, inducing degradation, cell cycle arrest, and apoptosis in prostate cancer models like 22Rv1 and LNCaP cells, with demonstrated in vivo anticancer activity.
CAS Number
3044108-04-2
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Smiles
O=C1C=2C=CC=C (NCCOC3=CC=C (C=C3) C (C4=CC=C (OCC5=NC (=CC=C5) N6CCOCC6) C=C4) (C) C) C2C (=O) N1C7C (=O) NC (=O) CC7
Molecular Formula
C40H41N5O7
Molecular Weight
703.783
Storage Conditions
-20°C
Notes
For research use only.