STING-IN-2

• Description :

  STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING) . STING-IN-2 can be used for autoinflammatory disease research[1].

• CAS Number :

  [346691-38-1]

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  STING

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/sting-in-2.html

• Purity :

  99.71

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(CCCC)C=C2

• Molecular Formula :

  C15H16N2O4

• Molecular Weight :

  288.30

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Simone M Haag, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559 (7713) :269-273.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported