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STING-IN-5

CAT: 0804-HY-152034-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-152034-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
STING-IN-5 is a potent STING inhibitor, inhibiting LPS-induced NO synthesis in macrophages with an IC50 value of 1.15 μM. STING-IN-5 inhibits the inflammatory response. STING-IN-5 can be used to research anti-inflammatory diseases and sepsis[1].
CAS Number
2920064-17-9
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sting-in-5.html
Purity
99.89
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@H]([C@H](OC(CCSSCCC(NOCC=C)=O)=O)CC[C@@]1([C@@]2([C@@H](C[C@]3(/C4=C(CC/C=C(C)/C)\C(OCC5=CC=CC=C5)=O)[H])O)[H])C)[C@@]1(CC[C@]2(C)[C@@]3(C)C[C@@H]4OC(C)=O)[H]
Molecular Formula
C47H67NO9S2
Molecular Weight
854.17
References & Citations
[1]Long J, et al. Discovery of fusidic acid derivatives as novel STING inhibitors for treatment of sepsis. Eur J Med Chem. 2022 Dec 15;244:114814.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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