STING-IN-9

• UNSPSC Description:

  STING-IN-9 (compound 2) is a potent inhibitor of human CYP11B2. STING-IN-9 showed more than 80 times higher selectivity over human CYP11B1 in vitro[1].

• Target Antigen:

  Mineralocorticoid Receptor

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Vitamin D Related/Nuclear Receptor

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/sting-in-9.html

• Smiles:

  N#CC1=CC=C(NC2=NC=NC=C2S(C(C)(C)CCCS(C)(=O)=O)(=O)=O)C=C1

• Molecular Weight:

  422.52

• References & Citations:

  [1]Masaki Meguro, et al. Identification of sulfonylpyrimidines as novel selective aldosterone synthase (CYP11B2) inhibitors. Bioorg Med Chem. 2024 Jun 15:108:117775.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported