STING-IN-9

• Description :

  STING-IN-9 (compound 2) is a potent inhibitor of human CYP11B2. STING-IN-9 showed more than 80 times higher selectivity over human CYP11B1 in vitro[1].

• UNSPSC :

  12352005

• Target :

  Mineralocorticoid Receptor

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Metabolic Disease

• Assay Protocol :

  https://www.medchemexpress.com/sting-in-9.html

• Smiles :

  N#CC1=CC=C(NC2=NC=NC=C2S(C(C)(C)CCCS(C)(=O)=O)(=O)=O)C=C1

• Molecular Formula :

  C18H22N4O4S2

• Molecular Weight :

  422.52

• References & Citations :

  [1]Masaki Meguro, et al. Identification of sulfonylpyrimidines as novel selective aldosterone synthase (CYP11B2) inhibitors. Bioorg Med Chem. 2024 Jun 15:108:117775.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported