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Antitumor agent-183

CAT: 0804-HY-159176Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-159176Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Antitumor agent-183 (compound 3f) has antitumor activity with metabolic stability. Antitumor agent-183 inhibits cancer cell growth, with IC50s less than 5 nM for A549, HCT116, and HS578T cells. The albumin-bound nanoparticle formulation of Antitumor agent-183 has prolonged retention in the tumor tissues[1].
CAS Number
2775428-94-7
UNSPSC
12352005
Target
Cytochrome P450
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(N[C@H]1CC(N(OC([2H])([2H])[2H])C([2H])([2H])[2H])=O)C2=CC(OC3=CC(C)=CC(C)=C3)=C(C=C2NC1=O)NC(C4=C(C(OC([2H])([2H])[2H])=C(C(OC([2H])([2H])[2H])=C4)OC([2H])([2H])[2H])Br)=O
Molecular Formula
C31H18D15BrN4O9
Molecular Weight
700.61
References & Citations
[1]Yu W, et al. Deuterium Editing of Small Molecules: A Case Study on Antitumor Activity of 1,4-Benzodiazepine-2,5-dione Derivatives. J Med Chem. 2024 Jul 18.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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