AV-412 free base

CAT: 0931-TQ0293Size: 2 mgDry Ice: NoHazardous: No

CAT#:0931-TQ0293Size:2 mg

Selected

PRICE

AVAILABILITY: InStock

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

1 / 1

CAS Number

451492-95-8

Target

EGFR

Related Pathways

Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

Bioactivity

AV-412 free base is an EGFR inhibitor (IC50s: 0.75, 0.79, 0.5, 2.3, 19 nM for EGFR, EGFR (T790M), EGFR (L858R), EGFR (L858R/T790M) and ErbB2) .

Smiles

CN1CCN(CC1)C(C)(C)C#Cc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C

Molecular Formula

C27H28ClFN6O

Molecular Weight

507

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Related Products