Products for Research Use Only
RegisterLogin

Atiprimod (free base)

CAT: 0931-T71176-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T71176-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
123018-47-3
Target
Others, PERK, ROS, JAK, ATG, Autophagy, STAT, p62, Apoptosis, NF-κB, Bcl-2 Family, Caspase, PARP
Related Pathways
JAK/STAT signaling, Stem Cells, NF-κB, Proteases/Proteasome, Others, Apoptosis, Tyrosine Kinase/Adaptors, Immunology/Inflammation, Chromatin/Epigenetic, DNA Damage/DNA Repair, Autophagy, Angiogenesis
Bioactivity
Atiprimod is an orally bioavailable small molecule belonging to the azaspirane class of cationic amphiphilic agents with anti-inflammatory, antineoplastic, and antiangiogenic properties. Atiprimod inhibits the phosphorylation of signal transducer and activator of transcription 3 (STAT3), blocking the signalling pathways of interleukin-6 and vascular endothelial growth factor (VEGF) and downregulating the anti-apoptotic proteins Bcl-2, Bcl-XL, and Mcl-1, thereby inhibiting cell proliferation, inducing cell cycle arrest, and inducing apoptosis.
Smiles
C(CCN(CC)CC)N1CC2(CCC(CCC)(CCC)CC2)CC1
Molecular Formula
C22H44N2
Molecular Weight
336.6
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T23761-01Atiprimod dimaleate
T35894-01Atiprimod dihydrochloride
T71012-01Nemazoline Free Base
T27970-01Mabuterol free base
T71491-01Enadoline (Free Base)
T71119-01Netarsudil free base
T70908-01EST64454 free base
T70793-01Parogrelil Free Base
T70555-01Tecalcet Free Base
T70381-01GSK2793660 free base

Alternative Products

CatalogName
MBS5813715Atiprimod (free base)
TB0954TMB free base
A8893-10Rucaparib (free base)
MBS5779607Amidantel free base
HY-164399ASST0116CL1 (free base)
HY-120475BPBT434 (free base)
FX56092-01Xylazine - free base
XN175452-01Norharman - free base
T-8100-01Tryptamine, free base
HY-119820Xaliproden (free base)

Popular Products