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Mabuterol free base

CAT: 0931-T27970-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T27970-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
56341-08-3
Target
Others, Adrenergic Receptor
Related Pathways
GPCR/G Protein, Neuroscience, Others
Bioactivity
Mabuterol is a selective agonist of β2 adrenoreceptor with no beta 1-stimulation. Mabuterol inhibited the positive inotropic effect of isoprenaline at 10 (-7) g/ml and decreased the maximum driving frequency at 3 X 10 (-6) g/ml. Mabuterol was 3 times more potent in relaxing the isolated rat uterus, but 700 times less potent than isoprenaline in relaxing the rabbit jejunum. Mabuterol (p.o.) depressed the intestinal propulsion and was equipotent to isoprenaline and 2.5 times less potent than salbutamol.
Smiles
FC(F)(F)C1=CC(=CC(Cl)=C1N)C(O)CNC(C)(C)C
Molecular Formula
C13H18ClF3N2O
Molecular Weight
310.74
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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