AV-412

• Target :

  EGFR

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors|||JAK/STAT signaling

• Purity :

  0.9992

• Bioactivity :

  AV-412 (MP412) is an EGFR inhibitor for EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M, and ErbB2, with IC50 values of 0.75, 0.79, 0.5, 2.3, and 19 nM, respectively.

• Smiles :

  Cc1ccc(cc1)S(O)(=O)=O.Cc1ccc(cc1)S(O)(=O)=O.CN1CCN(CC1)C(C)(C)C#Cc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=C

• Molecular Formula :

  C41H44ClFN6O7S2

• Molecular Weight :

  851.41

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  451493-31-5