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Enadoline (Free Base)

CAT: 0931-T71491-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T71491-01Size:25 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
107431-28-7
Target
Opioid Receptor|||Others
Related Pathways
Neuroscience|||Endocrinology/Hormones|||GPCR/G Protein|||Others
Bioactivity
Enadoline (Free Base) is a kappa-opioid receptor agonist; PD 129290 (CAM 570; CI 977) is the S, S (-) -enantiomer; PD 129289 (CAM 569) is the corresponding R, R (+) -enantiomer. In human studies, it produced visual distortions and feelings of dissociation, reminiscent of the effects of salvinorin A. It was studied as a potential analgesic, but abandoned because of the dose-limiting effects of dysphoria, which could be expected from a ?-opioid agonist. There was mention of its potential in treating comatose head injury or stroke victims, where that type of side effect would be immaterial.
Smiles
N(C(CC1=C2C(OC=C2)=CC=C1)=O)(C)C3C(CC4(CC3)CCCO4)N5CCCC5
Molecular Formula
C24H32N2O3
Molecular Weight
396.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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