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SNIPER (ABL) -044

CAT: 0931-T18691-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T18691-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, SNIPERs, Bcr-Abl
Related Pathways
Cytoskeletal Signaling, Others, Tyrosine Kinase/Adaptors, Angiogenesis, PROTAC
Bioactivity
SNIPER (ABL) -044, a compound that links HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, achieving a DC50 value of 10 μM[1].
Smiles
CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(C4=NC5=C(N=C(NC(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC6=CC=CC=C6)N)=O)=O)=O)S5)C=C4)=CC=C3)=O)C=C2)CC1
Molecular Formula
C51H64F3N9O8S
Molecular Weight
1020.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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