SNIPER (ABL) -044

• Target:

  Others|||SNIPERs|||Bcr-Abl

• Related Pathways:

  Cytoskeletal Signaling|||Others|||Tyrosine Kinase/Adaptors|||Angiogenesis|||PROTAC

• Bioactivity:

  SNIPER (ABL) -044, a compound that links HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, achieving a DC50 value of 10 ?M[1].

• Smiles:

  CCN1CCN (CC2=C (C (F) (F) F) C=C (NC (C3=CC (C4=NC5=C (N=C (NC (COCCOCCOCCNC ([C@H] (CC (C) C) NC ([C@@H] (O) [C@@H] (CC6=CC=CC=C6) N) =O) =O) =O) S5) C=C4) =CC=C3) =O) C=C2) CC1

• Molecular Formula:

  C51H64F3N9O8S

• Molecular Weight:

  1020.17

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C