SNIPER (ABL) -044

• Target:

  Others|||SNIPERs|||Bcr-Abl

• Related Pathways:

  Cytoskeletal Signaling|||Others|||Tyrosine Kinase/Adaptors|||Angiogenesis|||PROTAC

• Bioactivity:

  SNIPER (ABL) -044, a compound that links HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, achieving a DC50 value of 10 ?M[1].

• Smiles:

  CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(C4=NC5=C(N=C(NC(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC6=CC=CC=C6)N)=O)=O)=O)S5)C=C4)=CC=C3)=O)C=C2)CC1

• Molecular Formula:

  C51H64F3N9O8S

• Molecular Weight:

  1020.17

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C