SNIPER (ABL) -050

• Target:

  Others|||SNIPERs|||Bcr-Abl

• Related Pathways:

  PROTAC|||Tyrosine Kinase/Adaptors|||Others|||Angiogenesis|||Cytoskeletal Signaling

• Bioactivity:

  SNIPER (ABL) -050 is a chemical compound that combines Imatinib, an ABL inhibitor, with MV-1, an IAP ligand, using a linker. This conjugation results in the reduction of BCR-ABL protein[1].

• Smiles:

  CC1=CC=C(NC(C2=CC=C(CN3CCN(C(COCCOCCOCCNC([C@H](C(C4=CC=CC=C4)C5=CC=CC=C5)NC([C@H]6N(C([C@@H](NC([C@H](C)NC)=O)C7CCCCC7)=O)CCC6)=O)=O)=O)CC3)C=C2)=O)C=C1NC8=NC=CC(C9=CC=CN=C9)=N8

• Molecular Formula:

  C68H84N12O9

• Molecular Weight:

  1213.47

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C