SNIPER (ABL) -019

CAT: 0931-MF-0006715-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0006715-01Size:100 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Bcr-Abl|||Others|||SNIPERs
Related Pathways
Tyrosine Kinase/Adaptors|||Others|||PROTAC|||Cytoskeletal Signaling|||Angiogenesis
Bioactivity
SNIPER (ABL) -019, a compound that links Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, exhibiting a DC50 of 0.3 ?M[1].
Smiles
CC1=C(NC(C2=CN=C(NC3=CC(N4CCN(C(COCCOCCOCCNC([C@H](C(C5=CC=CC=C5)C6=CC=CC=C6)NC([C@H]7N(C([C@@H](NC([C@H](C)NC)=O)C8CCCCC8)=O)CCC7)=O)=O)=O)CC4)=NC(C)=N3)S2)=O)C(Cl)=CC=C1
Molecular Formula
C60H77ClN12O9S
Molecular Weight
1177.85
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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