SNIPER (ABL) -019

• Target:

  Bcr-Abl|||Others|||SNIPERs

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Others|||PROTAC|||Cytoskeletal Signaling|||Angiogenesis

• Bioactivity:

  SNIPER (ABL) -019, a compound that links Dasatinib (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels, exhibiting a DC50 of 0.3 ?M[1].

• Smiles:

  CC1=C(NC(C2=CN=C(NC3=CC(N4CCN(C(COCCOCCOCCNC([C@H](C(C5=CC=CC=C5)C6=CC=CC=C6)NC([C@H]7N(C([C@@H](NC([C@H](C)NC)=O)C8CCCCC8)=O)CCC7)=O)=O)=O)CC4)=NC(C)=N3)S2)=O)C(Cl)=CC=C1

• Molecular Formula:

  C60H77ClN12O9S

• Molecular Weight:

  1177.85

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C