SNIPER (ABL) -015

• Target:

  Bcr-Abl|||Others|||SNIPERs

• Related Pathways:

  Angiogenesis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors|||Others|||PROTAC

• Bioactivity:

  SNIPER (ABL) -015, a compound that conjugates GNF5 (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 5 ?M [1].

• Smiles:

  O=C(NCCOCCOCCOCCNC([C@@H](NC([C@H]1N(C([C@H](C2CCCCC2)NC([C@H](C)NC)=O)=O)CCC1)=O)C(C3=CC=CC=C3)C4=CC=CC=C4)=O)C5=CC=CC(C6=NC=NC(NC7=CC=C(OC(F)(F)F)C=C7)=C6)=C5

• Molecular Formula:

  C58H70F3N9O9

• Molecular Weight:

  1094.23

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C