Products for Research Use Only
RegisterLogin

SNIPER (ABL) -044

CAT: 0804-HY-111862Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-111862Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SNIPER (ABL) -044, conjugating HG-7-85-01 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 10 μM[1].
UNSPSC
12352005
Target
Bcr-Abl; SNIPERs
Type
Reference compound
Related Pathways
PROTAC; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sniper-abl-044.html
Solubility
10 mM in DMSO
Smiles
CCN1CCN(CC2=C(C(F)(F)F)C=C(NC(C3=CC(C4=NC5=C(N=C(NC(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC6=CC=CC=C6)N)=O)=O)=O)S5)C=C4)=CC=C3)=O)C=C2)CC1
Molecular Formula
C51H64F3N9O8S
Molecular Weight
1020.17
References & Citations
[1]Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108 (8) :1657-1666.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-111858SNIPER (ABL) -050
HY-111860SNIPER (ABL) -013
HY-111854SNIPER (ABL) -015
HY-111851SNIPER (ABL) -049
HY-111859SNIPER (ABL) -058
HY-111874SNIPER (ABL) -039
HY-111871SNIPER (ABL) -033
HY-111872-01SNIPER (ABL) -020
HY-111863SNIPER (ABL) -047
HY-111873SNIPER (ABL) -019

Alternative Products

CatalogName
MBS5771550SNIPER(ABL)-044
T18691-01SNIPER (ABL) -044
XND35461-01SNIPER (ABL) -058
XND35429-01SNIPER (ABL) -039
XND35418-01SNIPER (ABL) -033
T18688-01SNIPER (ABL) -024
MBS3844069-01SNIPER (ABL)-058
MBS3844060-01SNIPER (ABL)-024
MBS5771549SNIPER(ABL)-039
GTR19224981-01SNIPER (ABL) -013

Popular Products