Z-DEVD-R110

Z-DEVD-R110

• CAS Number: 223538-61-2
• UNSPSC Description: Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore[1].
• Target Antigen: Apoptosis; Caspase; Fluorescent Dye
• Type: Peptides
• Related Pathways: Apoptosis;Others
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/z-devd-r110.html
• Solubility: 10 mM in DMSO
• Smiles: [O-]C(C1=C(C=CC=C1)C2=C(C=CC(NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC(OCC3=CC=CC=C3)=O)=O)=O)=O)=O)=C4)C4=[O+]C5=C2C=CC(NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC(OCC6=CC=CC=C6)=O)=O)=O)=O)=O)=C5)=O
• Molecular Weight: 1515.44
• References & Citations: [1]Cheng X, et al. Apoptosis propagates through the cytoplasm as trigger waves. Science. 2018 Aug 10;361(6402):607-612.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported