Z-DEVD-CMK

Z-DEVD-CMK

• CAS Number: 250584-13-5
• UNSPSC Description: Z-DEVD-CMK is an irreversible inhibitor of most of the cathepsins in vitro[1].
• Target Antigen: Cathepsin
• Type: Peptides
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/z-devd-cmk.html
• Solubility: 10 mM in DMSO
• Smiles: CC([C@H](NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(O)=O)=O)CCC(O)=O)=O)C(N[C@H](C(CCl)=O)CC(O)=O)=O)C
• Molecular Weight: 643.04
• References & Citations: [1]Rozman-Pungercar J, et al. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 2003 Aug;10(8):881-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported