Z-DEVD-CMK

• Description :

  Z-DEVD-CMK is an irreversible inhibitor of most of the cathepsins in vitro[1].

• UNSPSC :

  12352209

• Target :

  Cathepsin

• Type :

  Peptides

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/z-devd-cmk.html

• Purity :

  98.99

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  CC([C@H](NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)CC(O)=O)=O)CCC(O)=O)=O)C(N[C@H](C(CCl)=O)CC(O)=O)=O)C

• Molecular Formula :

  C27H35ClN4O12

• Molecular Weight :

  643.04

• References & Citations :

  [1]Rozman-Pungercar J, et al. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 2003 Aug;10 (8) :881-8.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported

• CAS Number :

  [250584-13-5]