R110

• Product Name Alternative:

  N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine

• UNSPSC Description:

  R110 is a potent, competitive inhibitor of macrophage migration inhibitory factor 2 (MIF2) tautomerase with an IC50 of 15 μM. R110 has the potential for the research of cancer diseases[1].

• Target Antigen:

  Macrophage migration inhibitory factor (MIF)

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/r110.html

• Purity:

  99.90

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=C(N)SC(C2=CC=C(Cl)C=C2)=C1)NCCCC

• Molecular Weight:

  308.83

• References & Citations:

  [1]Xiao Z, et al. Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells. J Med Chem. 2022 Feb 10;65(3):2059-2077.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1985622-33-0