R110

• Description :

  R110 is a potent, competitive inhibitor of macrophage migration inhibitory factor 2 (MIF2) tautomerase with an IC50 of 15 μM. R110 has the potential for the research of cancer diseases[1].

• Product Name Alternative :

  N-Lauroyl-D-erythro-sphingosine; N-Laurylsphingosine

• UNSPSC :

  12352005

• Target :

  Macrophage migration inhibitory factor (MIF)

• Type :

  Reference compound

• Related Pathways :

  Immunology/Inflammation

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/r110.html

• Purity :

  99.90

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=C(N)SC(C2=CC=C(Cl)C=C2)=C1)NCCCC

• Molecular Formula :

  C15H17ClN2OS

• Molecular Weight :

  308.83

• References & Citations :

  [1]Xiao Z, et al. Thieno[2,3-d]pyrimidine-2,4 (1H,3H) -dione Derivative Inhibits d-Dopachrome Tautomerase Activity and Suppresses the Proliferation of Non-Small Cell Lung Cancer Cells. J Med Chem. 2022 Feb 10;65 (3) :2059-2077.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1985622-33-0]