Z-DEVD-R110

CAT: 0931-T87662-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T87662-01Size:10 mg
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CAS Number
223538-61-2
Target
Others|||Apoptosis|||Caspase
Related Pathways
Proteases/Proteasome|||Apoptosis|||Others
Bioactivity
Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp) 2 -Rhodamine 110), a rhodamine derivative featuring two four–amino acid (DEVD) peptides attached to the fluorophore [1], serves as a fluorogenic substrate for caspase-3/7. This compound is utilized for detecting apoptosis, leveraging its design to bind and indicate caspase activation.
Smiles
C([O-])(=O)C1=C(C=2C3=C([O+]=C4C2C=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC5=CC=CC=C5)=O)CC(O)=O)=O)CCC(O)=O)=O)[C@@H](C)C)=O)CC(O)=O)=O)=C4)C=C(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(OCC6=CC=CC=C6)=O)CC(O)=O)=O)CCC(O)=O)=O)C(C)C)=O)CC(O)=O)=O)C=C3)C=CC=C1
Molecular Formula
C72H78N10O27
Molecular Weight
1515.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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