Z-DEVD-AMC

CAT: 0804-HY-P3363-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-P3363-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates[1].
UNSPSC
12171500
Target
Caspase
Type
Dye Reagents
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/z-devd-amc.html
Purity
99.55
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
CC(C1=CC=C(NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)=O)C=C1O3)=CC3=O
Molecular Formula
C36H41N5O14
Molecular Weight
767.74
References & Citations
[1]Mauro C X Pinto, et al. Discovery of cytotoxic and pro-apoptotic compounds against leukemia cells: Tert-butyl-4-[ (3-nitrophenoxy) methyl]-2,2-dimethyloxazolidine-3-carboxylate. Life Sci. 2011 Nov 21;89 (21-22) :786-94.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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