Z-DEVD-AMC

• Description :

  Z-DEVD-AMC is a selective caspase-3 substrate that can be measured by fluorescence spectrometry. AMC can be used as a fluorescence reference standard for AMC-based enzyme substrates including AMC-based caspase substrates[1].

• UNSPSC :

  12171500

• Target :

  Caspase

• Type :

  Dye Reagents

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/z-devd-amc.html

• Purity :

  99.55

• Solubility :

  DMSO : 33.33 mg/mL (ultrasonic)

• Smiles :

  CC(C1=CC=C(NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)=O)C=C1O3)=CC3=O

• Molecular Formula :

  C36H41N5O14

• Molecular Weight :

  767.74

• References & Citations :

  [1]Mauro C X Pinto, et al. Discovery of cytotoxic and pro-apoptotic compounds against leukemia cells: Tert-butyl-4-[ (3-nitrophenoxy) methyl]-2,2-dimethyloxazolidine-3-carboxylate. Life Sci. 2011 Nov 21;89 (21-22) :786-94.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported