Z-DEVD-AFC

Z-DEVD-AFC

• CAS Number: 1135416-11-3
• UNSPSC Description: Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity[1].
• Target Antigen: Caspase
• Type: Dye Reagents
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/z-devd-afc.html
• Purity: 98.95
• Solubility: DMSO : 50 mg/mL (ultrasonic)
• Smiles: FC(F)(C(C1=CC=C(NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)=O)C=C1O3)=CC3=O)F
• Molecular Weight: 821.71
• References & Citations: [1]Santiago AR, et al. High glucose induces caspase-independent cell death in retinal neural cells. Neurobiol Dis. 2007;25(3):464-472.
• Shipping Conditions: Blue Ice
• Storage Conditions: -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported