Z-DEVD-AFC

• Description :

  Z-DEVD-AFC is a cell-permeant substrate for caspase-3, which causes a shift in fluorescence uponcleavage of the AFC fluorophore. Z-DEVD-AFC can be used to detect caspase-3-like enzymes activity[1].

• UNSPSC :

  12171500

• Target :

  Caspase

• Type :

  Dye Reagents

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/z-devd-afc.html

• Purity :

  98.08

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  FC(F)(C(C1=CC=C(NC([C@H](CC(O)=O)NC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CC(O)=O)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)=O)C=C1O3)=CC3=O)F

• Molecular Formula :

  C36H38F3N5O14

• Molecular Weight :

  821.71

• References & Citations :

  [1]Santiago AR, et al. High glucose induces caspase-independent cell death in retinal neural cells. Neurobiol Dis. 2007;25 (3) :464-472.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category :

  Dye Reagents

• Clinical Information :

  No Development Reported

• CAS Number :

  [1135416-11-3]