Antitumor agent-176

• Description:

  Antitumor agent-176 (Compound 22), an antitumor agent, can effectively bind to FGF2 and inhibit the activation of fibroblast growth factor receptor (FGFR) in multiple myeloma (MM) cells, exhibiting significant antitumor activity both in vivo and in vitro against MM[1].

• UNSPSC:

  12352005

• Target:

  FGFR

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/antitumor-agent-176.html

• Smiles:

  OC (C1=CC=C (C2=CC=C3C=C (O) C=CC3=C2) C=C1) CC (O) (C (F) (F) F) C (F) (F) F

• Molecular Formula:

  C21H16F6O3

• Molecular Weight:

  430.34

• References & Citations:

  [1]Taranto S, et al. Discovery of novel FGF trap small molecules endowed with anti-myeloma activity[J]. Pharmacological Research, 2024: 107291.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4