Apoptosis inducer 16

• Description:

  Apoptosis inducer 16 (Compound 3) is a bivalent Smac mimic that can effectively bind to BIR2 and BIR3, and exhibits cancer cell (apoptosis) inducing activity[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/apoptosis-inducer-16.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N(C[C@@H]1NC([C@@H](NC)C)=O)CC[C@](CC[C@H]2C(NC(C3=CC=CC=C3)C4=CC=CC=C4)=O)([H])N2C1=O)CCCCCCCC(N(C[C@@H]5NC([C@@H](NC)C)=O)CC[C@](CC[C@H]6C(NC(C7=CC=CC=C7)C8=CC=CC=C8)=O)([H])N6C5=O)=O

• Molecular Formula:

  C63H82N10O8

• Molecular Weight:

  1107.39

• References & Citations:

  [1]Huang Q, et al. Design, in silico evaluation, and in vitro verification of new bivalent Smac mimetics with pro-apoptotic activity. Methods. 2024;224:35-46.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported