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Apoptosis inducer 16

CAT: 0804-HY-161473Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161473Size:1 Each
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Description
Apoptosis inducer 16 (Compound 3) is a bivalent Smac mimic that can effectively bind to BIR2 and BIR3, and exhibits cancer cell (apoptosis) inducing activity[1].
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/apoptosis-inducer-16.html
Solubility
10 mM in DMSO
Smiles
O=C(N(C[C@@H]1NC([C@@H](NC)C)=O)CC[C@](CC[C@H]2C(NC(C3=CC=CC=C3)C4=CC=CC=C4)=O)([H])N2C1=O)CCCCCCCC(N(C[C@@H]5NC([C@@H](NC)C)=O)CC[C@](CC[C@H]6C(NC(C7=CC=CC=C7)C8=CC=CC=C8)=O)([H])N6C5=O)=O
Molecular Formula
C63H82N10O8
Molecular Weight
1107.39
References & Citations
[1]Huang Q, et al. Design, in silico evaluation, and in vitro verification of new bivalent Smac mimetics with pro-apoptotic activity. Methods. 2024;224:35-46.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported