Apoptosis inducer 44

• Description:

  Apoptosis inducer 44 is an apoptosis inducer. Apoptosis inducer 44 triggers apoptosis in MDA-MB-231 cells by increasing the levels of Bax and Cyt C, reducing Bcl-2, and initiating caspase-3 cleavage. Apoptosis inducer 44 suppresses the invasion and migration of MDA-MB-231 cells by down-regulating MMP-2 and MMP-9 expression and up-regulating E-cadherin protein levels. Apoptosis inducer 44 can be used for the study of breast cancer[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; Bcl-2 Family; Cadherin; Caspase; MMP

• Related Pathways:

  Apoptosis; Cytoskeleton; Metabolic Enzyme/Protease

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Smiles:

  OC1=CC=C (/C=C/C (C=C) (C) CC/C=C (C) \C) C=C1C (N2CCCCC2) C3=CC (F) =C (F) C (F) =C3

• Molecular Formula:

  C30H36F3NO

• Molecular Weight:

  483.61

• References & Citations:

  [1]Li HM, et al. Synthesis and anti-breast cancer evaluation of new bakuchiol derivatives. Bioorg Med Chem Lett. 2025 Dec 1;128:130361.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  Bax; Bcl-2; Caspase 3; MMP-2; MMP-9