Apoptosis inducer 44

• Description :

  Apoptosis inducer 44 is an apoptosis inducer. Apoptosis inducer 44 triggers apoptosis in MDA-MB-231 cells by increasing the levels of Bax and Cyt C, reducing Bcl-2, and initiating caspase-3 cleavage. Apoptosis inducer 44 suppresses the invasion and migration of MDA-MB-231 cells by down-regulating MMP-2 and MMP-9 expression and up-regulating E-cadherin protein levels. Apoptosis inducer 44 can be used for the study of breast cancer[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis; Bcl-2 Family; Cadherin; Caspase; MMP

• Related Pathways :

  Apoptosis; Cytoskeleton; Metabolic Enzyme/Protease

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Smiles :

  OC1=CC=C(/C=C/C(C=C)(C)CC/C=C(C)\C)C=C1C(N2CCCCC2)C3=CC(F)=C(F)C(F)=C3

• Molecular Formula :

  C30H36F3NO

• Molecular Weight :

  483.61

• References & Citations :

  [1]Li HM, et al. Synthesis and anti-breast cancer evaluation of new bakuchiol derivatives. Bioorg Med Chem Lett. 2025 Dec 1;128:130361.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Bax; Bcl-2; Caspase 3; MMP-2; MMP-9