Apoptosis inducer 48

• Description:

  Apoptosis inducer 48 (5d) is an apoptotic agent. Apoptosis inducer 48 inhibits the growth of triple-negative breast cancer cells. Apoptosis inducer 48 attenuates proteasomal degradation via the ubiquitin-proteasome pathway, leading to G2/M phase cell cycle arrest and the induction of apoptotic[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; E1/E2/E3 Enzyme

• Related Pathways:

  Apoptosis; Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C1/C(CN(C2CC2)C/C1=C\C3=CC=C(O)C(OC)=C3)=C/C4=CC=CC=C4

• Molecular Formula:

  C23H23NO3

• Molecular Weight:

  361.43

• References & Citations:

  [1]Khor PY, et al. Discovery of New Non-Symmetrical Heterocyclic Pentanoid Derivatives Targeting Metastatic Triple-Negative Breast Cancer. Bioorg Med Chem Lett. 2025 Aug 1;123:130232.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported