Apoptosis inducer 41

• Description:

  Apoptosis inducer 41 is an apoptosis inducer that induces apoptosis through the mitochondrial pathway. Apoptosis inducer 41 exhibits remarkable inhibitory effects against MCF-7 cells (IC50 = 6.2 μM) . Apoptosis inducer 41 significantly arrests MCF-7 cells in the G2/M phase, increases ROS accumulation, induces mitochondrial membrane potential depolarization. Apoptosis inducer 41 can used for the study of breast cancer[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis; Reactive Oxygen Species (ROS)

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research:

  Cancer

• Smiles:

  C[C@@]12[C@](C[C@@]3([H])[C@]2([H])[C@@H]([C@H](O3)CC[C@@H](C)C(NCC4=CN(N=N4)CC5=CC=C(C=C5)Br)=O)C)([H])[C@@]6([H])[C@]([C@@]7(C(C[C@H](CC7)OC(C)=O)=CC6)C)([H])CC1

• Molecular Formula:

  C39H53BrN4O4

• Molecular Weight:

  721.77

• References & Citations:

  [1]Huang X, et al. Synthesis and biological evaluation of diosgenin derivatives as potential anti-breast cancer agents. Bioorg Chem. 2025 Jul 26;164:108809.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3085940-57-1]