Apoptosis inducer 29

• Description:

  Apoptosis inducer 29 (compund Y9) is an apoptosis inducer that exhibits antitumor effects in non-small cell lung cancer. Apoptosis inducer 29 selectively acidifies lysosomes and induces lysosomal dysfunction, with superior potency to Gboixn (HY-111651) in vitro and in vivo.[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/apoptosis-inducer-29.html

• Smiles:

  CC1=C(C(C)=CC(C)=C1)CNC(C[N+]2=C(CC)N(CC(O[C@@H]3[C@@H](C(C)C)CC[C@H](C)C3)=O)C4=CC=CC=C42)=O.[Cl-]

• Molecular Formula:

  C33H46ClN3O3

• Molecular Weight:

  568.19

• References & Citations:

  [1]Yin J, et al. Y9, a Gboxin analog, displays anti-tumor effect in non-small cell lung cancer by inducing lysosomal dysfunction and apoptosis. Bioorg Chem. 2024 Dec;153:107820.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported