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Human IL-2 Protein

CAT: 0749-PRP1025-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0749-PRP1025-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin (IL-2) abbreviated as interleukin, refers to a lymphokine that interacts between leukocytes or immune cells, and it belongs to the same cytokine as blood cell growth factor. The two coordinate and interact with each other to complete hematopoietic and immune regulation functions together. Interleukins play an important role in transmitting information, activating and regulating immune cells, mediating the activation, proliferation and differentiation of T and B cells, and in inflammation.
Description
Human IL-2 protein, expressed in E. coli
Product Name Alternative
Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2
Gene ID
3558
Accession Number
P60568
Tag
IL-2
Type
Cytokines and proteins
Applications
No tag
Purity
> 98 % as determined by SDS-PAGE
Activity
Measured by its ability to induce proliferation in CTLL-2 cells.The ED50 for this effect is 2.269 ng/ml.
Molecular Weight
15.5 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized Human IL-2 protein protein product should be stored desiccated below-18°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below-18°C. For long term storage it is recommended to add a carrier protein (0.1% HSAor BSA) . Please prevent freeze-thaw cycles
Protein Length
The recombinant human IL-2 consists of 134 amino acids (N-Met) and has a predicted molecular mass of 15.5 KD. The apparent molecular mass of the human IL-2 is approximately 16 KD in SDS-PAGE under reducing conditions due to glycosylation.
Formulation
Lyophilized from sterile 20 mM Tris, 50 mM NaCl, pH 5.0, 1 mM DTT,1 mM EDTA
Applications Notes
Human
Other Product Names
Interleukin-2; IL-2; T-Cell Growth Factor; TCGF; Aldesleukin; IL2
Recommended Usage
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IL-2 protein protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions
Preparation
E. coli
Accession Number URL
https://www.uniprot.org/uniprot/P60568
AA Sequence
Amino acid sequence derived from human IL-2 isoform (P60568-1) (Ala21-Thr153) was expressed.

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