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Human IL-18 Protein

CAT: 0749-PRP1023-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0749-PRP1023-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-18 (IL-18) belongs to the IL-1 family. An intermediate molecule that induces the synthesis of interferon gamma. It can stimulate the proliferation of T cells, enhance the activity of natural killer cells, participate in the production of cytokines, and cooperate with IL-12.
Description
Human IL-18 protein, expressed in E. coli
Product Name Alternative
IL-18; IL18; IL 18; IFN gamma inducing factor; Interleukin 18; Interleukin-18; Interleukin 18 (interferon-gamma-inducing factor)
Gene ID
3606
Accession Number
Q14116
Tag
IL-18
Type
Cytokines and proteins
Applications
No tag
Purity
≥ 98 % as determined by SDS-PAGE
Activity
Testing in progress
Molecular Weight
18 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin: < 1 EU per μg of the protein as determined by the LAL method
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized Human IL-18 proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Protein Length
The recombinant Human IL-18 consists of 158 amino acids (N-Met) and has a predicted molecular mass of 18 kDa. The apparent molecular mass of the Human IL-18 protein is approximately 18 kDa in SDS-PAGE under reducing conditions
Formulation
Lyophilized from sterile 20 mM Tris, 150 mM NaCl pH 7.5.
Applications Notes
Human
Other Product Names
IL-18; IL18; IL 18; IFN gamma inducing factor; Interleukin 18; Interleukin-18; Interleukin 18 (interferon-gamma-inducing factor)
Recommended Usage
Always centrifuge tubes before opening . It is recommended to centrifuge at 12,000 rpm for 1 minute. Then reconstitute the lyophilized Human IL-18 protein with the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
Preparation
E. coli
Accession Number URL
https://www.uniprot.org/uniprot/Q14116
AA Sequence
Amino acid sequence derived from Human IL-18 isoform (Q14116) (Tyr37-Asp193) was expressed.

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