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Human IL-36β Protein

CAT: 0749-PRP1949-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0749-PRP1949-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Interleukin-36 beta (IL-36β) is an 18 kDa cytokine with 154 amino acid residues. IL-36β, the ligand of IL-36R, is expressed in keratinocytes and plays a significant role in inflammatory responses. IL-36β regulates biological functions like the differentiation of T cells. Moreover, IL-36β recruits neutrophils via inducing the expression of cytokines and chemokines, such as IL-17C, granulocyte colony-stimulating factor (G-CSF), IL-8, CXCL-1, and tumor necrosis factor (TNF) .
Description
IL-36β
Product Name Alternative
Il36b, Fil1e, Il1f8, Interleukin-36 beta, Interleukin-1 family member 8, IL-1F8
Gene ID
27177
Accession Number
Q9NZH7-2
Tag
IL-36β
Type
Cytokines and proteins
Applications
No tag
Purity
> 98 % as determined by SDS-PAGE
Activity
Testing in progress
Molecular Formula
17.37 kDa
Molecular Weight
17.37 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin : < 0.1 EU per μg of the protein as determined by the LAL method.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized recombinant Human IL-36β Protein product should be stored desiccated below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles.
Protein Length
The recombinant Human IL-36 beta consists of 160 amino acids and predicts a molecular mass of 17.37 KDa
Formulation
Lyophilized from sterile 20 mM Tris with 150 mM NaCl, pH 7.4.
Applications Notes
Human
Other Product Names
Il36b, Fil1e, Il1f8, Interleukin-36 beta, Interleukin-1 family member 8, IL-1F8
Recommended Usage
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant Human IL-36β Protein using the buffer we provided not less than 100µg/ml, which can then be further diluted to other aqueous solutions
Preparation
E.coli
Accession Number URL
https://www.uniprot.org/uniprotkb/Q9NZH7/entry#sequences
AA Sequence
Amino acid sequence derived from Human IL36β (Arg5-Glu164) (Q9NZH7) was expressed.

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