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Human IL-4 Protein

CAT: 0749-PRP1912-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0749-PRP1912-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Human Interleukin-4 (IL-4) is a cytokine that plays an important role in regulating inflammation and immuneresponses. It induces the differentiation of T cells to Th2 cells. This cytokine binds the IL-4 receptor that also binds another cytokine interleukin 13 (IL-13), which may explain the overlapping functions of IL-4 and IL-13.
Description
Human Interleukin-4 (IL-4) is a cytokine that plays an important role in regulating inflammation and immune responses. It induces the differentiation of T cells to Th2 cells. This cytokine binds the IL-4 receptor that also binds another cytokine interleukin 13 (IL-13), which may explain the overlapping functions of IL-4 and IL-13.
Product Name Alternative
IL-4; Interleukin 4; BCGF1; BSF1
Gene ID
3565
Accession Number
P05112
Tag
IL-4
Type
Cytokines and proteins
Applications
No tag
Purity
> 98 % as determined by SDS-PAGE
Activity
Measured by its ability to induce proliferation in TF-1 cells. The ED50 for this effect is 0.5308 ng/mL.
Molecular Weight
15.1 kDa
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits
Endotoxin: <1 EU per 1 μg of the protein by the LAL method.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Lyophilized protein product should be stored desiccated below -20°C. The protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) . Please prevent freeze-thaw cycles
Protein Length
The recombinant Human IL-4 consists of 129 amino acids and predicts a molecular mass of 15.1 kDa.
Formulation
The protein was liquid in from sterile 20 mM Tris-HCl, 150mM NaCl, 10% glycerol, pH8.0. If you have any concerns or special requirements, please confirm with us.
Applications Notes
Human
Other Product Names
IL-4; Interleukin 4; BCGF1; BSF1
Recommended Usage
Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized recombinant protein to a concentration of 0.1-1 mg/mL using the buffer we provided, and keep at room temperature for at least 20 min to fully dissolve. Please avoid vortex vigorously
Preparation
E. coli
Accession Number URL
https://www.uniprot.org/uniprotkb/P05112/entry
AA Sequence
Amino acid sequence derived from Human IL-4 (His25-Ser153) (P05112-1) was expressed.

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